Brotman Baty Institute Clinical

Variant Database (BBI-CVD)

About the BBI-CVD

The BBI-CVD aims to serve as a hub connecting researchers doing high-throughput functional studies and developing novel therapies with clinicians applying precision genomics to care for patients with rare diseases. Specifically, the BBI-CVD contains a repository of genetic variants encountered during clinical testing at the University of Washington and Fred Hutch Cancer Center.


Our full database contains extensive demographic, clinical, and genetic variant level information for each participant entered in our database. Deidentified phenotypic information associated with each of the variants in our database is available to researchers upon request. To assist researchers, we have created a secure web-based portal for viewing deidentified information within our database and can provide access to this to researchers upon request. Please email our team at, and we will follow up with the next steps. Access to identifiable information requires appropriate safeguards, including researchers having Institutional Review Board (IRB) approval for patient level data and consenting. Please email our team at, and we will follow up with the next steps.

Team Leadership:

Andrew B. Stergachis, MD PhD

Fuki Hisama, MD

Marianne Dubard-Gault, MD


Martha Horike-Pyne

Research Coordinators:

Eric Y. Kao

Database architect:

Adriana Sedeño Cortés, MSc

Jeremy Stone

Andrew Folta


This project is funded by the Brotman Baty Institute (BBI) and the National Human Genome Research Institute (R01HG013025).